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# When a bio chemical reaction is carried out in laboratory out side the human body in the absence of enzyme, then the rate of reaction obtained is $10^{–6}$ times, than activation energy of reaction in the presence of enzyme is : -

( A ) P is required
( B ) Different from, $E_a$ obtained in laboratery
( C ) $\frac{6}{RT}$
( D ) Can't say any thing