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Home  >>  JEEMAIN and AIPMT  >>  Biology  >>  Human Physiology
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Regarding Rh incompatibility and erythroblastosis foetalis - choose the incorrect option :


( A ) first child has the highest risk
( B ) erythroblastosis foetalis could be fatal to the foetus or could cause severe anaemia and jaundice to the baby
( C ) during the delivery of the first child, there is a possibility of exposure of the maternal blood to small amounts of the Rh+ve blood from the foetus and the mother starts preparing antibodies against Rh antigen in her blood
( D ) Rh antigens of the foetus do not get exposed to the Rh-ve blood of the mother in the first pregnancy as the two bloods are well separated by the placenta.
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1 Answer

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(A) is the right answer.

A special case of Rh incompatibility (mismatching) has been observed between the Rh-ve blood of a pregnant mother with Rh+ve blood of the foetus. Rh antigens of the foetus do not get exposed to the Rh-ve blood of the mother in the first pregnancy as the two bloods are well separated by the placenta. However, during the delivery of the first child, there is a possibility of exposure of the maternal blood to small amounts of the Rh+ve blood from the foetus. In such cases, the mother starts preparing antibodies against Rh antigen in her blood. In case of her subsequent pregnancies, the Rh antibodies from the mother (Rh-ve) can leak into the blood of the foetus (Rh+ve) and destroy the foetal RBCs. This could be fatal to the foetus or could cause severe anaemia and jaundice to the baby. This condition is called erythroblastosis foetalis. This can be avoided by administering anti-Rh antibodies to the mother immediately after the delivery of the first child. First child has the least risk and with increasing order of pregnancy risk increases.
answered Apr 3, 2014 by pady_1
 
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