# The reflection of the point $P(1,0,0)$ in the $\large\frac{x-1}{2} =\frac{y+1}{-3} =\frac{z+10}{8}$ is
$\begin{array}{1 1} (3,-4,-2) \\ (5,-8,-4) \\ (1,-1,-10) \\ (2,-3,8) \end{array}$