The equation of the chord of contact of tangents from $(2 , 1 )$ to the hyperbola $\large\frac{x^{2}}{16}-\frac{y^{2}}{9}$$=1$ is

Question

$$\begin{array}{1 1}(1)9x-8y-72=0&(2)9x+8y+72=0\\(3)8x-9y-72=0&(4)8x+9y+72=0\end{array}$$